Often case analysis develops in stages during the interview, and an evolving theory of the case guides the interview to uncover confirmatory information or take the emerging analysis in a different direction. In this fourth course in our Advanced Clinical Skills sequence, we present a series of successful case histories based on the interview and analytical methods presented in the first 3 courses, so that the vision of the successful case can help demonstrate the kind of information most important to elicit to develop an effective vitalist treatment plan.